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This is known as "Macrophage Polarization." The ability to shift from M1 to M2 efficiently is the Holy Grail of wound repair

Additionally, addressing factors such as alcohol use, smoking, and medications that impair absorption enhances treatment effectiveness

If you have a vitamin B12 deficiencyperhaps due to conditions like pernicious anemia, certain digestive disorders, or a strict vegan dietyou may experience symptoms such as fatigue, weakness, and low energy

Or they may find themselves B12 deficient for other reasons

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Precautions General Precautions: Vitamin B 12 deficiency that is allowed to progress for longer than 3 months may produce permanent degenerative lesions of the spinal cord